Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.62 |
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | MAX | P61244 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | GLB1 | P16278 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412135 | 1.00 | PIM1 (0.62) | PIM1MYCMAXPOLBSIRT2 | |
| SCHEMBL30442966 | 0.86 | HPGD (0.55) | PIM1MEN1KMT2AMAOAMAOB | |
| SCHEMBL15828894 | 0.81 | HPGD (0.59) | PIM1POLBMEN1KMT2AMAOA | |
| SCHEMBL31412140 | 0.81 | PIM1 (0.59) | PIM1MYCMAXMEN1KMT2A | |
| SCHEMBL29049326 | 0.81 | HPGD (0.59) | PIM1POLBMEN1KMT2AMAOA | |
| SCHEMBL15421861 | 0.78 | HPGD (0.59) | MEN1KMT2AMAOAMAOBHPGD | |
| SCHEMBL15421862 | 0.78 | HPGD (0.59) | MEN1KMT2AMAOAMAOBHPGD | |
| SCHEMBL29049322 | 0.78 | PIM1 (0.55) | PIM1MEN1KMT2AMAOAMAOB | |
| SCHEMBL15281015 | 0.78 | PIM1 (0.55) | PIM1MEN1KMT2AMAOAMAOB | |
| SCHEMBL2341294 | 0.78 | PIM1 (0.55) | PIM1MEN1KMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554079-B | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116554079-A | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-08-08 | — | — | CN | disclosed |