Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525578 | 1.00 | NAPRT (0.43) | NAPRTKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL30525582 | 0.82 | KDM4E (0.47) | KDM4ETDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL2558755 | 0.82 | KDM4E (0.47) | KDM4ETDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL3369832 | 0.80 | KDM4E (0.50) | NAPRTKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3220634 | 0.80 | HPGD (0.53) | KDM4ETDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL3788527 | 0.80 | MEN1 (0.60) | TDP1ALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL30525576 | 0.80 | P2RX7 (0.46) | KDM4ETDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL29049458 | 0.80 | P2RX7 (0.46) | KDM4ETDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL11782992 | 0.77 | MEN1 (0.50) | NAPRTKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11782258 | 0.77 | MKNK1 (0.55) | KDM4ETDP1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514769-B | 4-hydroxy pyrimidine-5-formylhydrazone derivative, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-116514769-A | 4-hydroxy pyrimidine-5-formylhydrazone derivative, preparation method, pharmaceutical composition and application | 中国药科大学 | 2023-08-01 | — | — | CN | disclosed |