Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.70 |
| ▸ | PDE5A | O76074 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900108 | 0.84 | ADORA1 (0.68) | ADORA1 | |
| Cartazolate SCHEMBL123839 | 0.83 | PDE4B (1.00) | PDE4BPDE5AMEN1MAPTBLM | |
| SCHEMBL2897824 | 0.82 | MEN1 (0.72) | PDE4BPDE5AMEN1MAPTBLM | |
| SCHEMBL2900207 | 0.81 | MEN1 (0.69) | PDE4BPDE5AMEN1MAPTBLM | |
| SCHEMBL5928041 | 0.78 | PDE4B (0.76) | PDE4BPDE5AMEN1MAPTBLM | |
| Ether SCHEMBL11843441 | 0.77 | PDE4B (0.75) | PDE4BPDE5AMEN1MAPTBLM | |
| SCHEMBL2897837 | 0.77 | ADORA1 (0.75) | ADORA1 | |
| SCHEMBL11786785 | 0.77 | PDE4B (0.74) | PDE4BPDE5AMEN1MAPTBLM | |
| Tracazolate SCHEMBL114769 | 0.76 | MEN1 (1.00) | PDE4BPDE5AMEN1MAPTBLM | |
| SCHEMBL13987140 | 0.76 | PDE4B (0.72) | PDE4BPDE5AMEN1MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982704-B1 | New molecular target of neurotoxicity | EXONHIT THERAPEUTICS SA (FR) | 2010-08-04 | — | — | EP | claimed |