Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752488 | 0.99 | HTR2C (0.55) | HTR2CHTR2AHTR6PLGPLAU | |
| Lithium SCHEMBL30527867 | 0.97 | HTR2C (0.54) | HTR2CHTR2AHTR6PLGPLAU | |
| SCHEMBL6754275 | 0.90 | PLG (0.51) | HTR2CHTR2APLGPLAUPLA2G4A | |
| SCHEMBL18960579 | 0.89 | HTR2C (0.56) | HTR2CHTR2AHTR6PLGPLAU | |
| SCHEMBL30443765 | 0.87 | HTR2C (0.58) | HTR2CHTR2AHTR6HTR1DNOS3 | |
| Lithium Ion SCHEMBL27175191 | 0.85 | HTR2C (0.52) | HTR2CHTR2AHTR6PLGPLAU | |
| SCHEMBL16741925 | 0.84 | HTR2A (0.54) | HTR2CHTR2AHTR6PLGPLAU | |
| SCHEMBL30527841 | 0.84 | HTR2A (0.54) | HTR2CHTR2AHTR6PLGPLAU | |
| SCHEMBL4934703 | 0.82 | PLA2G4A (0.55) | PLGPLAUPLA2G4AALDH1A1RAPGEF4 | |
| SCHEMBL1663734 | 0.81 | TP53 (0.47) | PLGPLAUPLA2G4AALDH1A1BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568303-A | Dihydrofuranopyridine derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2023-08-08 | — | — | CN | disclosed |