Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 2/20 | 0.33 |
| ▸ | CHKB | Q9Y259 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24538478 | 0.82 | PDCD1 (0.36) | GRM5PDCD1CD274ATRNPC1 | |
| SCHEMBL14930362 | 0.77 | PDE10A (0.44) | GRM5PDCD1CD274ATRPDE1B | |
| SCHEMBL30916111 | 0.77 | GRM5 (0.40) | GRM5PDCD1CD274PDE1BKCNH2 | |
| SCHEMBL11888242 | 0.75 | PDCD1 (0.47) | GRM5PDCD1CD274CHKACHKB | |
| SCHEMBL21452254 | 0.75 | PDCD1 (0.42) | GRM5PDCD1CD274 | |
| SCHEMBL21452258 | 0.74 | PDCD1 (0.52) | PDCD1CD274ATRF10 | |
| SCHEMBL23109923 | 0.74 | RAD52 (0.40) | GRM5PDCD1CD274NPC1RAB9A | |
| SCHEMBL14925519 | 0.74 | GRM5 (0.40) | GRM5PDCD1CD274ATRPDE1B | |
| SCHEMBL28895700 | 0.74 | GRM5 (0.44) | GRM5NPC1RAB9A | |
| SCHEMBL1251008 | 0.74 | F10 (0.50) | GRM5F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568303-A | Dihydrofuranopyridine derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2023-08-08 | — | — | CN | disclosed |