Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23109923 | 0.75 | RAD52 (0.40) | GRM5PDCD1CD274PDE1BKCNH2 | |
| SCHEMBL14925519 | 0.75 | GRM5 (0.40) | GRM5PDCD1CD274PDE1BKCNH2 | |
| Lithium Ion SCHEMBL27175184 | 0.75 | GRM5 (0.38) | GRM5PDCD1CD274PDE1BKCNH2 | |
| SCHEMBL24538478 | 0.70 | PDCD1 (0.36) | GRM5PDCD1CD274 | |
| SCHEMBL30916103 | 0.68 | RAD52 (0.41) | GRM5 | |
| SCHEMBL23699915 | 0.67 | PDK1 (0.56) | — | |
| SCHEMBL30916117 | 0.67 | RAD52 (0.40) | GRM5 | |
| SCHEMBL14817814 | 0.65 | GRM5 (0.32) | GRM5 | |
| SCHEMBL24585187 | 0.65 | CYP3A4 (0.45) | — | |
| SCHEMBL18375024 | 0.65 | GRM5 (0.38) | GRM5PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936475-B | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-111936475-B | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |