Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 8/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391938 | 1.00 | MAP4K4 (0.38) | MAP4K4PIK3CAPIK3CDPIP5K1CPIK3CB | |
| SCHEMBL29698555 | 1.00 | MAP4K4 (0.38) | MAP4K4PIK3CAPIK3CDPIP5K1CPIK3CB | |
| SCHEMBL29050370 | 0.86 | KCNH2 (0.34) | MAP4K4PIK3CAEGFRMTORPDE10A | |
| SCHEMBL31391781 | 0.86 | KCNH2 (0.34) | MAP4K4PIK3CAEGFRMTORPDE10A | |
| SCHEMBL23878377 | 0.84 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL23878643 | 0.84 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL30977935 | 0.84 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL23878487 | 0.84 | MAP4K4 (0.34) | MAP4K4 | |
| SCHEMBL30977837 | 0.84 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL4507986 | 0.79 | MAP4K4 (0.41) | MAP4K4PIK3CAPIK3CDPIP5K1CPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528857-A | MALT-1 modulators | 艾克斯赛安西娅人工智能有限公司 | 2023-08-01 | — | — | CN | disclosed |