SCHEMBL30977935

SCHEMBL30977935

COC(C)c1c(N)cnc2ccc(Cl)nc12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23878377 1.00 PIK3CD (0.30) PIK3CD
SCHEMBL23878643 1.00 PIK3CD (0.30) PIK3CD
SCHEMBL30977837 1.00 PIK3CD (0.30) PIK3CD
SCHEMBL23878487 0.85 MAP4K4 (0.34)
SCHEMBL31391938 0.84 MAP4K4 (0.38) PIK3CD
SCHEMBL29050347 0.84 MAP4K4 (0.38) PIK3CD
SCHEMBL29698555 0.84 MAP4K4 (0.38) PIK3CD
SCHEMBL25283465 0.84 MELK (0.32) PIK3CD
SCHEMBL25239879 0.84 MELK (0.32) PIK3CD
SCHEMBL23878654 0.79 MERTK (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420620-A Heterocyclic compounds 武田药品工业株式会社 2024-08-02 CN disclosed
CN-113038948-B Heterocyclic compounds 武田药品工业株式会社 2024-07-12 CN disclosed