Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083000 | 0.90 | TACR1 (0.47) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2842365 | 0.90 | TACR1 (0.47) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2838269 | 0.90 | TACR1 (0.47) | TACR1PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL2581220 | 0.89 | TACR1 (0.46) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2837927 | 0.87 | TACR1 (0.47) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1029043 | 0.87 | TACR1 (0.47) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2846210 | 0.87 | TACR1 (0.47) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1723646 | 0.81 | RAB9A (0.48) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1723644 | 0.81 | RAB9A (0.48) | TACR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1723643 | 0.81 | RAB9A (0.48) | TACR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105807-B | Hydroxycyclohexanamide compound and preparation method and application thereof | 暨南大学 | 2023-08-18 | — | — | CN | claimed |
| CN-114105807-A | Hydroxycyclohexane diamide compound and preparation method and application thereof | 暨南大学 | 2022-03-01 | — | — | CN | claimed |
| CN-114105807-B | Hydroxycyclohexanamide compound and preparation method and application thereof | 暨南大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-114105807-A | Hydroxycyclohexane diamide compound and preparation method and application thereof | 暨南大学 | 2022-03-01 | — | — | CN | disclosed |