Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780908 | 0.89 | PARP1 (0.36) | ALDH1A1GAAPKMKCNJ6KCNJ5 | |
| SCHEMBL29052540 | 0.86 | MAPT (0.43) | ALDH1A1GAAKDM4EPANK3SORT1 | |
| SCHEMBL30513338 | 0.86 | CNR1 (0.41) | ALDH1A1GAAKDM4EKCNJ6KCNJ5 | |
| SCHEMBL29052209 | 0.86 | CNR1 (0.41) | ALDH1A1GAAKDM4EKCNJ6KCNJ5 | |
| SCHEMBL29781023 | 0.86 | MAPT (0.43) | ALDH1A1GAAKDM4EPANK3SORT1 | |
| SCHEMBL29052180 | 0.83 | CNR1 (0.44) | ALDH1A1GAAKDM4EPKMKCNJ6 | |
| SCHEMBL29052193 | 0.73 | CNR1 (0.41) | KDM4EKCNJ6KCNJ5KCNJ3KMT2A | |
| SCHEMBL29781088 | 0.73 | CNR1 (0.41) | KDM4EKCNJ6KCNJ5KCNJ3KMT2A | |
| SCHEMBL29052606 | 0.73 | CNR1 (0.41) | ALDH1A1GAAKDM4EPANK3 | |
| SCHEMBL15279151 | 0.73 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4EPKMSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583287-A | Pyridazinone heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2022166610-A1 | PYRIDAZINONE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-08-11 | — | — | WO | disclosed |