Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24229758 | 0.88 | HRH3 (0.47) | HRH3CYP2D6HRH1 | |
| SCHEMBL29052789 | 0.84 | HRH3 (0.48) | HRH3CYP2D6HRH1 | |
| SCHEMBL24229492 | 0.80 | HRH3 (0.44) | HRH3CYP2D6HRH1 | |
| SCHEMBL24229708 | 0.79 | HRH3 (0.43) | HRH3CYP2D6HRH1 | |
| SCHEMBL24229635 | 0.78 | HRH3 (0.41) | HRH3CYP2D6HRH1 | |
| SCHEMBL24229494 | 0.74 | HRH3 (0.54) | HRH3CYP2D6HRH1 | |
| SCHEMBL24229760 | 0.73 | — | — | |
| SCHEMBL24229756 | 0.70 | HDAC6 (0.56) | HRH3CYP2D6HRH1 | |
| SCHEMBL24229711 | 0.67 | TDP1 (0.34) | CYP2D6HRH1 | |
| SCHEMBL3089244 | 0.67 | HRH3 (0.74) | HRH3CYP2D6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601150-A | Fused bicyclic RAF inhibitors and methods of use thereof | 爵士制药爱尔兰有限公司 | 2023-08-15 | — | — | CN | disclosed |