Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30570719 | 1.00 | HSD17B10 (0.53) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| SCHEMBL7263223 | 0.88 | HSD17B10 (0.51) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| SCHEMBL4241160 | 0.86 | DRD3 (0.60) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7262142 | 0.82 | HSD17B10 (0.61) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| SCHEMBL30539981 | 0.82 | HSD17B10 (0.61) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL11027379 | 0.79 | HSD17B10 (0.83) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL30570718 | 0.79 | HSD17B10 (0.83) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| SCHEMBL28559532 | 0.77 | HSD17B10 (0.58) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| SCHEMBL7262101 | 0.77 | GAA (0.42) | HSD17B10DRD3KDM4EALDH1A1MEN1 | |
| SCHEMBL12877362 | 0.77 | KDM4E (0.52) | HSD17B10KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824389-B | Acrylic ketone derivative of N-acetylnorfloxacin and preparation method and application thereof | 河南大学 | 2023-08-15 | — | — | CN | disclosed |