Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200120 | 0.85 | KDM4E (0.74) | KDM4EKMT2ATDP1ATMALDH1A1 | |
| SCHEMBL29053157 | 0.77 | HSD17B10 (0.53) | KDM4EKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL30570719 | 0.77 | HSD17B10 (0.53) | KDM4EKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL4241160 | 0.74 | DRD3 (0.60) | KDM4EKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7263223 | 0.74 | HSD17B10 (0.51) | KDM4EKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL15281352 | 0.73 | KDM4E (0.62) | KDM4EKMT2ATDP1ATMALDH1A1 | |
| SCHEMBL7262142 | 0.71 | HSD17B10 (0.61) | KDM4EKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL30539981 | 0.71 | HSD17B10 (0.61) | KDM4EKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL12877366 | 0.70 | KDM4E (0.57) | KDM4EKMT2ATDP1ATMALDH1A1 | |
| SCHEMBL7294536 | 0.70 | ALDH1A1 (0.54) | KDM4EKMT2ATDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046142-A1 | ANTIBIOTIC COMPOUNDS | NORTHEASTERN UNIVERSITY (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046142-A1 | ANTIBIOTIC COMPOUNDS | AADAC, SPOUT1, NRDC | KDM4E 2212/4885KMT2A 3535/4885TDP1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.