Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 7/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588912 | 0.92 | CASP3 (0.55) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL29401236 | 0.92 | CASP3 (0.55) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL31348963 | 0.92 | CASP3 (0.55) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL31348914 | 0.92 | CASP3 (0.55) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL29401206 | 0.92 | CASP3 (0.55) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL29053258 | 0.89 | CASP3 (0.58) | CASP3MDM4TP53KMT2A | |
| SCHEMBL15886222 | 0.86 | HDAC1 (0.51) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL15883745 | 0.85 | HDAC1 (0.48) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL31348948 | 0.85 | HDAC1 (0.48) | CASP3MDM4TP53HDAC1HDAC2 | |
| SCHEMBL31348954 | 0.85 | HDAC1 (0.48) | CASP3MDM4TP53HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478324-B | Active compound and application thereof in side chain carboxyl compound protection | 上海嘉莱多生物技术有限责任公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-114478324-A | Active compound and application thereof in side chain carboxyl compound protection | 上海嘉莱多生物技术有限责任公司 | 2022-05-13 | — | — | CN | disclosed |