Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | BACE1 | P56817 | 2/20 | 0.64 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 13/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.58 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23726540 | 0.87 | TLR9 (0.65) | ACHEBACE1ENPP1AURKAPDGFRB | |
| SCHEMBL30080209 | 0.87 | TLR9 (0.65) | ACHEBACE1ENPP1AURKAPDGFRB | |
| Hydrochloric Acid SCHEMBL2915718 | 0.86 | ACHE (0.80) | ACHEBACE1ENPP1AURKAPDGFRB | |
| SCHEMBL4726710 | 0.84 | ENPP1 (0.65) | ACHEBACE1ENPP1AURKAPDGFRB | |
| SCHEMBL22631414 | 0.83 | ACHE (0.67) | ACHEBACE1ENPP1AURKAPDGFRB | |
| SCHEMBL29055085 | 0.83 | PDGFRB (0.69) | ACHEBACE1ENPP1AURKAPDGFRB | |
| SCHEMBL25656495 | 0.83 | ENPP1 (0.59) | ACHEBACE1ENPP1AURKAPDGFRB | |
| SCHEMBL23762347 | 0.83 | ENPP1 (0.85) | ACHEBACE1ENPP1AURKA | |
| Hydrochloric Acid SCHEMBL23726065 | 0.82 | ENPP1 (0.84) | ACHEBACE1ENPP1AURKA | |
| Hydrochloric Acid SCHEMBL30079993 | 0.82 | ENPP1 (0.84) | ACHEBACE1ENPP1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362145-A | Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) inhibitors and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-11-18 | — | — | CN | disclosed |