Dexborneol

Dexborneol

SCHEMBL2905504

CC1(C)[C@@H]2CC[C@@]1(C)[C@@H](O)C2.CC1=CCC2C(C1)C2(C)C

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CYP19A1 P11511 2/20 0.30
CYP2C19 P33261 1/20 0.30
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Borneol SCHEMBL2905507 1.00 KMT2A (0.34) KMT2AMAPTMAPK1GRIN2DGRIN3B
Dexborneol SCHEMBL3507513 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
Dexborneol SCHEMBL9303298 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
Dexborneol SCHEMBL3622754 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
(-)-Borneol SCHEMBL839194 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
Dexborneol SCHEMBL23849409 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
Dexborneol SCHEMBL5031066 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
Dexborneol SCHEMBL20576252 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
Borneol SCHEMBL20576251 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1
Dexborneol SCHEMBL14236488 0.75 EPHX2 (0.41) KMT2AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1463482-B1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STABILIZING DIBENZOYLMETHANE AVON PROD INC (US) 2010-08-11 EP claimed
US-7186404-B2 Photostable sunscreen compositions and methods of stabilizing AVON PRODUCTS, INC. (US) 2007-03-06 US claimed
US-20050186159-A1 Photostable sunscreen compositions and methods of stabilizing AVON PRODUCTS, INC. 2005-08-25 US claimed
EP-1463482-A4 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PROD INC (US) 2005-03-16 EP claimed
EP-1463482-A1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PRODUCTS, INC. (US) 2004-10-06 EP claimed
US-20030124070-A1 Photostable sunscreen compositions and methods of stabilizing AVON PRODUCTS INC. 2003-07-03 US claimed
WO-2003051318-A1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PRODUCTS, INC. (US) 2003-06-26 WO claimed
EP-1463482-B1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STABILIZING DIBENZOYLMETHANE AVON PROD INC (US) 2010-08-11 EP disclosed
US-7186404-B2 Photostable sunscreen compositions and methods of stabilizing AVON PRODUCTS, INC. (US) 2007-03-06 US disclosed
US-20050186159-A1 Photostable sunscreen compositions and methods of stabilizing AVON PRODUCTS, INC. 2005-08-25 US disclosed
EP-1463482-A4 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PROD INC (US) 2005-03-16 EP disclosed
EP-1463482-A1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PRODUCTS, INC. (US) 2004-10-06 EP disclosed
US-20030124070-A1 Photostable sunscreen compositions and methods of stabilizing AVON PRODUCTS INC. 2003-07-03 US disclosed
WO-2003051318-A1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PRODUCTS, INC. (US) 2003-06-26 WO disclosed
US-6440402-B1 Photostable sunscreen compositions and methods of stabilizing AVON PRODUCTS, INC. 2002-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050186159-A1 Photostable sunscreen compositions and methods of stabilizing GLA, TYR, GANAB KMT2A 274/4885MAPT 653/4885MAPK1 3104/4885
US-20030124070-A1 Photostable sunscreen compositions and methods of stabilizing GLA, LAGE3, CYP51A1 KMT2A 233/4885MAPT 895/4885MAPK1 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.