Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 14/20 | 0.42 |
| ▸ | HTR1D | P28221 | 4/20 | 0.38 |
| ▸ | HTR1B | P28222 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055282 | 0.92 | FGFR4 (0.42) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055283 | 0.90 | FGFR4 (0.41) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055273 | 0.90 | HTR1D (0.39) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055285 | 0.88 | FGFR4 (0.39) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055280 | 0.81 | HTR1D (0.35) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055281 | 0.81 | HTR1D (0.35) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055294 | 0.80 | RORC (0.33) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055279 | 0.80 | HTR1D (0.34) | FGFR4HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL29055287 | 0.80 | RORC (0.33) | FGFR4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29055292 | 0.79 | CNR2 (0.34) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635390-A | Potent and selective compounds as serotonin 1B receptor modulators | 莱科斯生物技术公司 | 2023-08-22 | — | — | CN | claimed |
| CN-116635390-A | Potent and selective compounds as serotonin 1B receptor modulators | 莱科斯生物技术公司 | 2023-08-22 | — | — | CN | disclosed |