SCHEMBL290556

SCHEMBL290556

O=C1C[CH]CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72417 0.81
SCHEMBL6101053 0.79
SCHEMBL250800 0.79
SCHEMBL7738689 0.77 TRIM24 (0.50)
SCHEMBL4276887 0.77
SCHEMBL7739749 0.77 TRIM24 (0.50)
SCHEMBL388722 0.73
SCHEMBL19875838 0.71
SCHEMBL1401055 0.71
SCHEMBL54268 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 636 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290322-A Aromatic molecules for the treatment of pathological conditions 赛尼欧普罗有限责任公司 2024-07-05 CN claimed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN claimed
US-20240140895-A1 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2024-05-02 US claimed
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2023-05-11 US claimed
US-20220354949-A1 NOVEL COMPOUNDS Xeniopro GmbH (DE) 2022-11-10 US claimed
CN-113999206-B Isoquinoline-1, 3-diamine analogue, preparation method, pharmaceutical composition and application thereof 北京鑫开元医药科技有限公司 2022-04-12 CN claimed
CN-113999206-A Isoquinoline-1, 3-diamine analogue, preparation method, pharmaceutical composition and application thereof 北京鑫开元医药科技有限公司 2022-02-01 CN claimed
CN-113754636-A Quinazoline-containing aza-ether compounds 湖南化工研究院有限公司 2021-12-07 CN claimed
EP-3841091-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY Xeniopro GmbH (DE) 2021-06-30 EP claimed
EP-3840834-A2 AROMATIC MOLECULES FOR USE IN THE TREATMENT OF PATHOLOGICAL CONDITIONS Xeniopro GmbH (DE) 2021-06-30 EP claimed
EP-1633692-A2 CYCLOHEXYL DERIVATIVES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-03-15 EP claimed
WO-2006016194-A1 SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS PROSIDION LIMITED (GB) 2006-02-16 WO claimed
WO-2005103021-A1 TRI(CYCLO) SUBSTITUTED AMIDE COMPOUNDS PROSIDION LIMITED (GB) 2005-11-03 WO claimed
CN-1649859-A Substituted phenylacetamides and their use as glucokinase activators HOFFMANN LA ROCHE (CH) 2005-08-03 CN claimed
EP-1501815-A1 SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2005-02-02 EP claimed
US-20050009799-A1 Cyclohexyl derivatives as selective estrogen receptor modulators JANSSEN PHARMACEUTICA N.V. (BE) 2005-01-13 US claimed
WO-2005000775-A2 CYCLOHEXYL DERIVATIVES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2005-01-06 WO claimed
WO-2003095438-A9 SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS HOFFMANN LA ROCHE (CH) 2004-12-23 WO claimed
WO-2003095438-A1 SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2003-11-20 WO claimed
US-5696124-A Xanthine derivatives with adenosine-antagonistic activity BOEHRINGER INGELHEIM KG (DE) 1997-12-09 US claimed