Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056268 | 0.94 | PDE4B (0.54) | PDE4BPDE4DSLC22A12BRAFKDR | |
| SCHEMBL29056216 | 0.88 | PDE4B (0.56) | PDE4BPDE4DBRAFKDR | |
| SCHEMBL30542663 | 0.88 | PDE4B (0.56) | PDE4BPDE4DBRAFKDR | |
| SCHEMBL29056196 | 0.86 | PDE4B (0.48) | PDE4BPDE4DCYP2C9CYP2C19BRAF | |
| SCHEMBL30542646 | 0.86 | PDE4B (0.48) | PDE4BPDE4DCYP2C9CYP2C19BRAF | |
| SCHEMBL29056261 | 0.83 | SLC22A12 (0.49) | PDE4BPDE4DSLC22A12CYP1A2CYP2C9 | |
| SCHEMBL29056212 | 0.80 | PDE4B (0.45) | PDE4BPDE4DSLC22A12CYP1A2CYP2C9 | |
| SCHEMBL29056200 | 0.79 | PDE4B (0.50) | PDE4BPDE4DSLC22A12 | |
| SCHEMBL29056255 | 0.79 | PDE4B (0.50) | PDE4BPDE4D | |
| SCHEMBL30542648 | 0.79 | PDE4B (0.50) | PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640095-A | Diaryl amine derivative containing aliphatic carboxyl and preparation method and application thereof | 山东大学 | 2023-08-25 | — | — | CN | disclosed |