Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542663 | 1.00 | PDE4B (0.56) | PDE4BPDE4DKDRBRAFPPARA | |
| SCHEMBL29056268 | 0.90 | PDE4B (0.54) | PDE4BPDE4DKDRBRAF | |
| SCHEMBL29056274 | 0.88 | PDE4B (0.53) | PDE4BPDE4DKDRBRAF | |
| SCHEMBL30542646 | 0.84 | PDE4B (0.48) | PDE4BPDE4DKDRBRAF | |
| SCHEMBL29056196 | 0.84 | PDE4B (0.48) | PDE4BPDE4DKDRBRAF | |
| SCHEMBL30542629 | 0.82 | PDE4B (0.50) | PDE4BPDE4DPPARA | |
| SCHEMBL30542648 | 0.82 | PDE4B (0.50) | PDE4BPDE4DPPARAPPARG | |
| SCHEMBL29056255 | 0.82 | PDE4B (0.50) | PDE4BPDE4DPPARAPPARG | |
| SCHEMBL29056200 | 0.82 | PDE4B (0.50) | PDE4BPDE4DPPARA | |
| SCHEMBL29056201 | 0.81 | PDE4B (0.47) | PDE4BPDE4DKDRBRAFPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640095-A | Diaryl amine derivative containing aliphatic carboxyl and preparation method and application thereof | 山东大学 | 2023-08-25 | — | — | CN | disclosed |