Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.68 |
| ▸ | MGAM | O43451 | 5/20 | 0.68 |
| ▸ | SI | P14410 | 5/20 | 0.68 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.68 |
| ▸ | PARP1 | P09874 | 7/20 | 0.59 |
| ▸ | TNKS | O95271 | 3/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967798 | 0.85 | DHODH (0.56) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL5938 | 0.85 | DHODH (0.56) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL29056753 | 0.84 | GAA (0.69) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL29056620 | 0.83 | MGAM (0.51) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL8818559 | 0.82 | GAA (0.69) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL29056651 | 0.80 | MGAM (0.48) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL3286051 | 0.80 | HDAC6 (0.60) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL29056720 | 0.80 | PARP1 (0.62) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL9694398 | 0.79 | KDM4E (0.55) | GAAMGAMSIMGAM2PARP1 | |
| SCHEMBL8818775 | 0.78 | GAA (0.64) | GAAMGAMSIMGAM2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |