Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057521 | 0.87 | ALDH1A1 (0.65) | OGAALDH1A1DRD4 | |
| SCHEMBL27008589 | 0.87 | OGA (0.79) | OGASMN1; SMN2ALDH1A1 | |
| SCHEMBL29057474 | 0.85 | ALDH1A1 (0.61) | OGASMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL29057543 | 0.85 | OGA (0.71) | OGASMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL29057507 | 0.81 | OGA (0.66) | OGAALDH1A1KMT2A | |
| SCHEMBL29057435 | 0.81 | ALDH1A1 (0.69) | OGASMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL29057479 | 0.81 | OGA (0.72) | OGAALDH1A1LMNAMAPTTSHR | |
| SCHEMBL29057489 | 0.80 | OGA (0.64) | OGAALDH1A1MEN1KMT2A | |
| SCHEMBL30439671 | 0.79 | OGA (0.59) | OGAALDH1A1LMNAMAPTTSHR | |
| SCHEMBL29057488 | 0.79 | OGA (0.59) | OGAALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438167-A | Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof | 美迪福伦DBT有限公司 | 2023-07-14 | — | — | CN | disclosed |