SCHEMBL29057448

SCHEMBL29057448

C=CC(=O)Nc1ncc(CN2CCN(CC(=O)Nc3ccc(C)cc3)CC2)s1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OGA O60502 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29057520 0.91 OGA (0.76) OGA
SCHEMBL29057418 0.90 OGA (0.63) OGA
SCHEMBL27022304 0.88 OGA (0.92) OGA
SCHEMBL29057484 0.85 OGA (0.60) OGA
SCHEMBL29057529 0.85 OGA (0.79) OGA
SCHEMBL29057538 0.84 OGA (0.61) OGA
SCHEMBL27008587 0.83 OGA (1.00) OGA
SCHEMBL29057507 0.81 OGA (0.66) OGA
SCHEMBL29057490 0.80 OGA (0.81) OGA
SCHEMBL27022312 0.80 OGA (1.00) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438167-A Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof 美迪福伦DBT有限公司 2023-07-14 CN disclosed