Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 14/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27008685 | 0.88 | OGA (0.76) | OGA | |
| SCHEMBL29057520 | 0.86 | OGA (0.76) | OGALMNASMN1; SMN2 | |
| SCHEMBL29057448 | 0.85 | OGA (0.71) | OGA | |
| SCHEMBL29057418 | 0.83 | OGA (0.63) | OGA | |
| SCHEMBL29057538 | 0.83 | OGA (0.61) | OGALMNASMN1; SMN2 | |
| SCHEMBL29057493 | 0.82 | MEN1 (0.56) | OGAMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29057471 | 0.79 | OGA (0.55) | OGASMN1; SMN2 | |
| SCHEMBL27008568 | 0.76 | OGA (0.72) | OGALMNASMN1; SMN2 | |
| SCHEMBL29057490 | 0.76 | OGA (0.81) | OGA | |
| SCHEMBL29057487 | 0.76 | OGA (0.61) | OGAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438167-A | Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof | 美迪福伦DBT有限公司 | 2023-07-14 | — | — | CN | disclosed |