Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.51 |
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | BTK | Q06187 | 5/20 | 0.48 |
| ▸ | ITK | Q08881 | 2/20 | 0.46 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.45 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058482 | 0.90 | AR (0.51) | CRBNARBTKITKIL2 | |
| SCHEMBL29597385 | 0.89 | CRBN (0.55) | CRBNARBTKITKIRAK1 | |
| Trifluoroacetic Acid SCHEMBL29058476 | 0.87 | CRBN (0.57) | CRBNARBTKITKIL2 | |
| SCHEMBL29058484 | 0.87 | CRBN (0.54) | CRBNARBTKITKIRAK1 | |
| SCHEMBL30488998 | 0.87 | CRBN (0.54) | CRBNARBTKITKIRAK1 | |
| SCHEMBL31605511 | 0.85 | AR (0.65) | CRBNARBTKIRAK1IRAK4 | |
| SCHEMBL31605518 | 0.85 | AR (0.65) | CRBNARBTKIRAK1IRAK4 | |
| Trifluoroacetic Acid SCHEMBL23705577 | 0.85 | CRBN (0.60) | CRBNARBTKITKIL2 | |
| SCHEMBL24299580 | 0.84 | CRBN (0.59) | CRBNARBTKIRAK1IRAK4 | |
| Trifluoroacetic Acid SCHEMBL27039552 | 0.84 | CRBN (0.59) | CRBNARBTKITKIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010858-B | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-112010858-A | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2020-12-01 | — | — | CN | disclosed |