Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 6/20 | 0.44 |
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30535116 | 0.89 | KRAS (0.42) | DDB1CRBNACACBGPR119 | |
| SCHEMBL29058455 | 0.86 | GPR119 (0.45) | DDB1CRBNNAMPTACACBGPR119 | |
| SCHEMBL31306762 | 0.85 | DDB1 (0.45) | DDB1CRBNNAMPTACACBGPR119 | |
| SCHEMBL26981235 | 0.85 | DDB1 (0.45) | DDB1CRBNNAMPTACACBGPR119 | |
| SCHEMBL14662465 | 0.85 | DDB1 (0.45) | DDB1CRBNNAMPTACACBGPR119 | |
| SCHEMBL590396 | 0.85 | DDB1 (0.55) | DDB1CRBNGPR119 | |
| SCHEMBL20396064 | 0.83 | DDB1 (0.43) | DDB1CRBNNAMPTACACBGPR119 | |
| SCHEMBL20396112 | 0.83 | DDB1 (0.43) | DDB1CRBNNAMPTACACBGPR119 | |
| SCHEMBL25628785 | 0.83 | DDB1 (0.43) | DDB1CRBNNAMPTACACBGPR119 | |
| SCHEMBL21063634 | 0.82 | USP30 (0.43) | DDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010858-B | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-112010858-A | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2020-12-01 | — | — | CN | disclosed |