Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 16/20 | 0.62 |
| ▸ | INSR | P06213 | 4/20 | 0.62 |
| ▸ | IGF1R | P08069 | 4/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059829 | 0.92 | ALK (0.60) | ALKINSRIGF1RMAP3K7EGFR | |
| Hydrochloric Acid SCHEMBL29059662 | 0.89 | EGFR (0.67) | ALKINSRIGF1REGFR | |
| Hydrochloric Acid SCHEMBL29059862 | 0.86 | ALK (0.61) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25870332 | 0.85 | ALK (0.60) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL29059911 | 0.85 | EGFR (0.66) | ALKINSRIGF1REGFR | |
| SCHEMBL29059669 | 0.85 | EGFR (0.62) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25304856 | 0.85 | EGFR (0.69) | ALKINSRIGF1RMAP3K7EGFR | |
| Hydrochloric Acid SCHEMBL29059831 | 0.85 | ALK (0.63) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL29059827 | 0.83 | ALK (0.77) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL29059698 | 0.83 | ALK (0.64) | ALKINSRIGF1RMAP3K7EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490184-A | Compounds for inhibiting EGFR mutant cancers and pharmaceutical uses thereof | J2H生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |