Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060782 | 1.00 | MAPT (0.74) | MAPTL3MBTL1TDP1KDM4EMAPK1 | |
| SCHEMBL19294487 | 0.85 | KDM4E (1.00) | MAPTL3MBTL1TDP1KDM4EMAPK1 | |
| SCHEMBL19299717 | 0.85 | KDM4E (0.82) | MAPTL3MBTL1TDP1KDM4EMAPK1 | |
| SCHEMBL6720185 | 0.83 | MAPT (1.00) | MAPTL3MBTL1TDP1KDM4EMAPK1 | |
| SCHEMBL22523761 | 0.82 | MAPT (0.82) | MAPTL3MBTL1TDP1KDM4EMAPK1 | |
| SCHEMBL2053346 | 0.79 | MAPT (0.79) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL979280 | 0.79 | MAPT (0.79) | MAPTMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL4029206 | 0.78 | HDAC2 (0.76) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL29060766 | 0.78 | HDAC2 (0.76) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL30008092 | 0.78 | MAPT (0.58) | MAPTL3MBTL1TDP1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606247-A | Imide compound and preparation method and application thereof | 温州医科大学 | 2023-08-18 | — | — | CN | disclosed |