SCHEMBL30008092

SCHEMBL30008092

O=C(NCC=Cc1ccccc1)c1ccco1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.58
MAPK1 P28482 1/20 0.58
RAB9A P51151 4/20 0.57
NPC1 O15118 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
ALDH1A1 P00352 8/20 0.57
HPGD P15428 2/20 0.57
KDM4E B2RXH2 3/20 0.54
TDP1 Q9NUW8 1/20 0.54
PKM P14618 1/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
POLB P06746 1/20 0.51
MAOA P21397 1/20 0.51
MAOB P27338 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.50
TNIK Q9UKE5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314305 0.78 ALDH1A1 (0.64) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9542310 0.78 NPC1 (0.56) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL9790512 0.78 NPC1 (0.56) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL29060780 0.78 MAPT (0.74) MAPTMAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL29060782 0.78 MAPT (0.74) MAPTMAPK1RAB9ANPC1SMN1; SMN2
SCHEMBL5123738 0.76 ALDH1A1 (0.77) MAPTRAB9ANPC1SMN1; SMN2L3MBTL1
SCHEMBL10619606 0.76 MAOB (0.61) MAPTSMN1; SMN2ALDH1A1KDM4EMEN1
SCHEMBL1694508 0.76 MAOB (0.61) MAPTSMN1; SMN2ALDH1A1KDM4EMEN1
SCHEMBL1582564 0.76 MAOB (0.61) MAPTSMN1; SMN2ALDH1A1KDM4EMEN1
SCHEMBL9790467 0.75 MAPT (0.56) MAPTRAB9ANPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105408-B Novel asymmetric catalytic nucleophilic fluorine heterocyclic reaction system and application thereof in chiral unnatural amino acid module synthesis 深圳市图微安创科技开发有限公司 2022-10-04 CN disclosed