Bicarbonate

SCHEMBL29061109

O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3A GSK3B IMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CA4	P22748	5/20	0.67

▸	FAHD1	Q6P587	1/20	0.67

▸	CA1	P00915	2/20	0.60

▸	MEN1	O00255	1/20	0.50

▸	LDHA	P00338	1/20	0.50

▸	BLM	P54132	1/20	0.50

▸	KMT2A	Q03164	1/20	0.50

▸	LMNA	P02545	2/20	0.46

▸	CASP1	P29466	1/20	0.46

▸	FFAR3	O14843	1/20	0.38

▸	HDAC3	O15379	1/20	0.38

▸	HDAC1	Q13547	1/20	0.38

▸	HDAC2	Q92769	1/20	0.38

▸	HDAC8	Q9BY41	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Bicarbonate SCHEMBL714912	1.00	CA4 (0.67)	CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL25	1.00	—	—
Bicarbonate SCHEMBL28582066	1.00	CA4 (0.67)	CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL1331273	1.00	—	—
Bicarbonate SCHEMBL2121875	1.00	CA4 (0.67)	CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL1331459	1.00	—	—
Bicarbonate SCHEMBL23849739	0.94	CA4 (0.60)	CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL17477711	0.94	CA4 (0.60)	CA4FAHD1CA1MEN1LDHA
Bicarbonate SCHEMBL8206114	0.94	—	—
Bicarbonate SCHEMBL77648	0.94	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115397959-A	Water-glycol hydraulic fluid composition and auxiliary additive thereof	国际壳牌研究有限公司	2022-11-25	—	—	CN	disclosed