Aceglumate

Aceglumate

SCHEMBL29061503

CC(=O)NC(CCC(=O)O)C(=O)O.CC(C)=CC(=O)NCC(=O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.51
NAALAD2 Q9Y3Q0 4/20 0.51
RIMKLA Q8IXN7 1/20 0.51
FNTA P49354 2/20 0.50
FNTB P49356 2/20 0.50
GNPAT O15228 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40
PTGS2 P35354 1/20 0.40
THPO P40225 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetylglutamic Acid SCHEMBL716411 0.81 FOLH1 (0.69) FOLH1NAALAD2RIMKLAFNTAFNTB
Acetylglutamic Acid SCHEMBL82128 0.81 FOLH1 (0.69) FOLH1NAALAD2RIMKLAFNTAFNTB
Aceglumate SCHEMBL198970 0.81 FOLH1 (0.69) FOLH1NAALAD2RIMKLAFNTAFNTB
Acetylglutamic Acid SCHEMBL2512801 0.81 FOLH1 (0.69) FOLH1NAALAD2RIMKLAFNTAFNTB
SCHEMBL13287551 0.80 FOLH1 (0.74) FOLH1NAALAD2RIMKLA
SCHEMBL18145912 0.80 FOLH1 (0.74) FOLH1NAALAD2RIMKLA
Acetylglutamic Acid SCHEMBL11403051 0.79 FOLH1 (0.67) FOLH1NAALAD2RIMKLAFNTAFNTB
Acetylglutamic Acid SCHEMBL11403044 0.79 FOLH1 (0.67) FOLH1NAALAD2RIMKLAFNTAFNTB
Aceglumate SCHEMBL11403040 0.79 FOLH1 (0.67) FOLH1NAALAD2RIMKLAFNTAFNTB
Acetylglutamic Acid SCHEMBL31621384 0.79 FOLH1 (0.67) FOLH1NAALAD2RIMKLAFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116685338-A Compositions and methods for improving skin health and for treating and preventing diseases, disorders and conditions associated with fungi and other pathogenic microorganisms 德慕拜昂生物科技公司 2023-09-01 CN disclosed