Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.69 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.69 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GNPAT | O15228 | 1/20 | 0.54 |
| ▸ | GGH | Q92820 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 2/20 | 0.50 |
| ▸ | FNTB | P49356 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylglutamic Acid SCHEMBL82128 | 1.00 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Acetylglutamic Acid SCHEMBL2512801 | 1.00 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Aceglumate SCHEMBL198970 | 1.00 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Acetylglutamic Acid SCHEMBL31621391 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Acetylglutamic Acid SCHEMBL11403044 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Acetylglutamic Acid SCHEMBL31621403 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Acetylglutamic Acid SCHEMBL11793383 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Acetylglutamic Acid SCHEMBL31621384 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Aceglumate SCHEMBL11403040 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| Acetylglutamic Acid SCHEMBL11403051 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117789993-A | Establishment and application of gastric cancer prediction model based on tongue fur metabolite | 浙江省肿瘤医院 | 2024-03-29 | — | — | CN | claimed |
| CN-115876826-A | Method for judging absolute configuration of oseltamivir | 北京格林意锐医药科技有限责任公司 | 2023-03-31 | — | — | CN | claimed |
| CN-107778234-B | Preparation method of neuromuscular blocker intermediate | 四川科瑞德制药股份有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115090225-A | Novel efficient aldehyde-removing transparent gel and preparation method thereof | 重庆中科力泰高分子材料股份有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-114716375-A | Preparation method of tetrahydrobenzyl isoquinoline compound | 四川科瑞德制药股份有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-113984814-A | Method for determining structure and absolute configuration of chiral sample by using MicroED technology | 无锡佰翱得生物科学有限公司 | 2022-01-28 | — | — | CN | claimed |
| EP-2183201-B1 | PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS | ESTEVE QUIMICA SA (ES) | 2012-03-28 | — | — | EP | claimed |
| US-7968712-B2 | Process for the resolution of zopiclone and intermediate compounds | ESTEVE QUIMICA, S.A. (ES) | 2011-06-28 | — | — | US | claimed |
| US-20100274018-A1 | PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS | ESTEVE QUIMICA, S.A. (ES) | 2010-10-28 | — | — | US | claimed |
| US-7772396-B2 | Process for the resolution of zopiclone and intermediate compounds | Esteve Quimica, S.A. Avda. Mare de deu de Monsterrat (ES) | 2010-08-10 | — | — | US | claimed |
| CN-101772475-A | Method and intermediate compounds for resolving zopiclone | ESTEVE QUIMICA SA | 2010-07-07 | — | — | CN | claimed |
| EP-2183201-A1 | PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS | Esteve Química, S.A. (ES) | 2010-05-12 | — | — | EP | claimed |
| WO-2009016251-A1 | PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS | Esteve Química, S.A. (ES) | 2009-02-05 | — | — | WO | claimed |
| US-20090036681-A1 | PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS | ESTEVE QUIMICA, S.A. (ES) | 2009-02-05 | — | — | US | claimed |
| EP-2020403-A1 | Process for the resolution of zopiclone and intermediate compounds | ESTEVE QUIMICA, S.A. (ES) | 2009-02-04 | — | — | EP | claimed |
| CN-1874992-A | Resolution of 3-amino alkylnitriles | PFIZER (US) | 2006-12-06 | — | — | CN | claimed |
| EP-1689703-A1 | RESOLUTION OF 3-AMINO ALKYLNITRILES | Pfizer Products Inc. (US) | 2006-08-16 | — | — | EP | claimed |
| US-7026345-B2 | Resolution of 3-amino alkylnitriles | PFIZER INC. (US) | 2006-04-11 | — | — | US | claimed |
| US-20050107453-A1 | Resolution of 3-amino alkylnitriles | PFIZER INC. | 2005-05-19 | — | — | US | claimed |
| WO-2005040097-A1 | RESOLUTION OF 3-AMINO ALKYLNITRILES | PFIZER PRODUCTS INC. (US) | 2005-05-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274018-A1 | PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS | CYP3A5, ZP1, AZI2 | FOLH1 1911/4885NAALAD2 629/4885RIMKLA 528/4885 |
| US-20050107453-A1 | Resolution of 3-amino alkylnitriles | AADAT, AANAT, AAAS | FOLH1 3707/4885NAALAD2 13/4885RIMKLA 11/4885 |
| US-20090036681-A1 | PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS | CYP3A5, ZP1, AZI2 | FOLH1 1911/4885NAALAD2 629/4885RIMKLA 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.