Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 19/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061671 | 1.00 | DGAT2 (0.75) | DGAT2KMT2A | |
| SCHEMBL25432851 | 0.91 | DGAT2 (0.75) | DGAT2KMT2A | |
| SCHEMBL27211673 | 0.91 | DGAT2 (0.75) | DGAT2KMT2A | |
| SCHEMBL25432848 | 0.91 | DGAT2 (0.75) | DGAT2KMT2A | |
| SCHEMBL29703024 | 0.85 | DGAT2 (1.00) | DGAT2KMT2A | |
| SCHEMBL25352109 | 0.85 | DGAT2 (1.00) | DGAT2KMT2A | |
| SCHEMBL25352105 | 0.85 | DGAT2 (1.00) | DGAT2KMT2A | |
| SCHEMBL29511935 | 0.85 | DGAT2 (1.00) | DGAT2KMT2A | |
| SCHEMBL29703101 | 0.85 | DGAT2 (1.00) | DGAT2KMT2A | |
| SCHEMBL27211677 | 0.85 | DGAT2 (1.00) | DGAT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685577-A | Preparation of benzimidazolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-09-01 | — | — | CN | claimed |
| CN-116685577-A | Preparation of benzimidazolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-09-01 | — | — | CN | disclosed |