Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 18/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352504 | 0.92 | DGAT2 (0.77) | DGAT2KMT2AATM | |
| SCHEMBL29511902 | 0.92 | DGAT2 (0.77) | DGAT2KMT2AATM | |
| SCHEMBL27211623 | 0.89 | DGAT2 (0.73) | DGAT2KMT2AATM | |
| SCHEMBL25352200 | 0.89 | DGAT2 (0.73) | DGAT2KMT2AATM | |
| SCHEMBL27211643 | 0.89 | DGAT2 (0.73) | DGAT2KMT2AATM | |
| SCHEMBL29511941 | 0.89 | DGAT2 (0.80) | DGAT2KMT2AATM | |
| SCHEMBL25349605 | 0.89 | DGAT2 (0.80) | DGAT2KMT2AATM | |
| SCHEMBL29061634 | 0.88 | DGAT2 (0.65) | DGAT2KMT2AATM | |
| SCHEMBL32663107 | 0.86 | DGAT2 (1.00) | DGAT2 | |
| SCHEMBL29512127 | 0.86 | DGAT2 (0.76) | DGAT2KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685577-A | Preparation of benzimidazolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-09-01 | — | — | CN | claimed |
| CN-116685577-A | Preparation of benzimidazolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-09-01 | — | — | CN | disclosed |