Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | RHEB | Q15382 | 3/20 | 0.44 |
| ▸ | MAP2 | P11137 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743428 | 0.87 | RHEB (0.51) | FLT3RHEBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24021051 | 0.85 | FLT3 (0.44) | FLT3ALDH1A1KDM4EHSD17B10HRH4 | |
| SCHEMBL16031847 | 0.84 | FLT3 (0.43) | FLT3RHEBMAP2ALDH1A1KDM4E | |
| SCHEMBL4785003 | 0.84 | KMT2A (0.54) | FLT3RHEBMAP2ALDH1A1KDM4E | |
| SCHEMBL29738295 | 0.82 | FLT3 (0.44) | FLT3RHEBMAP2ALDH1A1KDM4E | |
| SCHEMBL24028985 | 0.81 | ALOX15 (0.53) | FLT3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29063225 | 0.80 | RHEB (0.42) | FLT3RHEBMAP2ALDH1A1KDM4E | |
| SCHEMBL29063128 | 0.79 | RHEB (0.47) | FLT3RHEBMAP2ALDH1A1KDM4E | |
| SCHEMBL29062784 | 0.73 | KDM4E (0.57) | FLT3RHEBMAP2ALDH1A1KDM4E | |
| SCHEMBL20505087 | 0.73 | FLT3 (0.57) | FLT3RHEBMAP2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |