Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 5/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | IL2 | P60568 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009402 | 1.00 | MEN1 (0.54) | MEN1KMT2ARCE1CTSBCTSL | |
| SCHEMBL24021127 | 1.00 | MEN1 (0.54) | MEN1KMT2ARCE1CTSBCTSL | |
| SCHEMBL29063309 | 0.92 | MEN1 (0.57) | MEN1KMT2ARCE1CTSBCTSL | |
| SCHEMBL24021128 | 0.92 | MEN1 (0.57) | MEN1KMT2ARCE1CTSBCTSL | |
| SCHEMBL30310539 | 0.92 | MEN1 (0.57) | MEN1KMT2ARCE1CTSBCTSL | |
| SCHEMBL24021129 | 0.86 | CTSB (0.65) | CTSBCTSLCTSS | |
| SCHEMBL30008375 | 0.86 | CTSB (0.65) | CTSBCTSLCTSS | |
| SCHEMBL30174726 | 0.83 | KMT2A (0.55) | MEN1KMT2ARCE1CTSBCTSL | |
| SCHEMBL28951850 | 0.83 | KMT2A (0.55) | MEN1KMT2ARCE1CTSBCTSL | |
| SCHEMBL25533122 | 0.83 | KMT2A (0.55) | MEN1KMT2ARCE1CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |