Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.80 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466328 | 1.00 | LANCL2 (0.80) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| SCHEMBL25311738 | 1.00 | LANCL2 (0.80) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| SCHEMBL25314522 | 0.93 | LANCL2 (0.70) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| SCHEMBL29466320 | 0.93 | LANCL2 (0.73) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| SCHEMBL25313429 | 0.93 | LANCL2 (0.73) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL25311498 | 0.92 | LANCL2 (0.71) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL29466273 | 0.92 | LANCL2 (0.71) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| SCHEMBL25312836 | 0.89 | LANCL2 (0.64) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| SCHEMBL25262280 | 0.89 | LANCL2 (0.64) | LANCL2HRH4RAB9AKDM4ENPC1 | |
| Omilancor SCHEMBL17706588 | 0.89 | LANCL2 (1.00) | LANCL2HRH4RAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670137-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022127774-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-23 | — | — | WO | disclosed |