Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.57 |
| ▸ | KDM4A | O75164 | 6/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29063575 | 1.00 | ALDH1A1 (0.65) | ALDH1A1TSHRDNM1SIGMAR1KDM4A | |
| Bromide SCHEMBL29063564 | 1.00 | ALDH1A1 (0.65) | ALDH1A1TSHRDNM1SIGMAR1KDM4A | |
| Bromide SCHEMBL29063574 | 1.00 | ALDH1A1 (0.65) | ALDH1A1TSHRDNM1SIGMAR1KDM4A | |
| Bromide SCHEMBL9491844 | 1.00 | ALDH1A1 (0.65) | ALDH1A1TSHRDNM1SIGMAR1KDM4A | |
| Bromide SCHEMBL7639265 | 0.97 | — | — | |
| SCHEMBL21246956 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRDNM1SIGMAR1KDM4A | |
| SCHEMBL11716299 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRDNM1SIGMAR1KDM4A | |
| SCHEMBL14531094 | 0.97 | — | — | |
| SCHEMBL28356106 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRDNM1SIGMAR1KDM4A | |
| SCHEMBL28285178 | 0.97 | ALDH1A1 (0.69) | ALDH1A1TSHRDNM1SIGMAR1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693747-A | Viscosity-increasing type temperature-resistant salt-tolerant polymer filtrate reducer and preparation method and application thereof | 长江大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116693747-A | Viscosity-increasing type temperature-resistant salt-tolerant polymer filtrate reducer and preparation method and application thereof | 长江大学 | 2023-09-05 | — | — | CN | disclosed |