Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.34 |
| ▸ | LCK | P06239 | 8/20 | 0.34 |
| ▸ | EGFR | P00533 | 7/20 | 0.34 |
| ▸ | ITK | Q08881 | 6/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064219 | 1.00 | BTK (0.34) | BTKLCKEGFRITKJAK3 | |
| SCHEMBL28097469 | 0.85 | BTK (0.39) | BTKLCKEGFRITKJAK3 | |
| SCHEMBL29064397 | 0.76 | BTK (0.39) | BTKLCKEGFRITKJAK3 | |
| SCHEMBL29064399 | 0.76 | BTK (0.39) | BTKLCKEGFRITKJAK3 | |
| SCHEMBL15516738 | 0.74 | PDE8B (0.40) | BTK | |
| SCHEMBL15516736 | 0.74 | PDE8B (0.40) | BTK | |
| SCHEMBL13860102 | 0.74 | HRH3 (0.35) | BTKLCKEGFRITKJAK3 | |
| SCHEMBL15562988 | 0.72 | BTK (0.37) | BTKLCKEGFRITKJAK3 | |
| SCHEMBL29063731 | 0.72 | FGFR2 (0.45) | BTKKDR | |
| SCHEMBL29063726 | 0.72 | FGFR2 (0.45) | BTKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514806-A | Biological inhibitor containing acrylketone, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |