Phthalic Acid

Phthalic Acid

SCHEMBL29064574

CCOC(=O)c1cccc2cccc(C(=O)OCC)c12.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
CDC25B P30305 2/20 0.57
ALDH1A1 P00352 5/20 0.54
MAPT P10636 5/20 0.54
HSD17B10 Q99714 3/20 0.54
KDM4E B2RXH2 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
CDC25A P30304 1/20 0.54
CDC25C P30307 1/20 0.54
CYP1A2 P05177 2/20 0.50
ALOX15 P16050 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MAPK10 P53779 1/20 0.50
PTK2B Q14289 1/20 0.50
NCOA1 Q15788 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741671 0.95 TSHR (0.59) TSHRCDC25BALDH1A1MAPTHSD17B10
SCHEMBL3681837 0.92 TSHR (0.68) TSHRCDC25BALDH1A1MAPTHSD17B10
Naphthalene SCHEMBL27469240 0.88 TSHR (0.75) TSHRCDC25BALDH1A1MAPTHSD17B10
SCHEMBL18526159 0.86 TSHR (0.66) TSHRCDC25BALDH1A1MAPTHSD17B10
Diethyl Phthalate SCHEMBL9132522 0.86 TSHR (0.84) TSHRCDC25BALDH1A1MAPTHSD17B10
SCHEMBL50234 0.86 TSHR (0.84) TSHRCDC25BALDH1A1MAPTHSD17B10
Diethyl Phthalate SCHEMBL28274022 0.86 TSHR (0.84) TSHRCDC25BALDH1A1MAPTHSD17B10
Phthalic Acid SCHEMBL9132525 0.86 TSHR (0.84) TSHRCDC25BALDH1A1MAPTHSD17B10
SCHEMBL29628800 0.86 TSHR (0.84) TSHRCDC25BALDH1A1MAPTHSD17B10
Diethyl Phthalate SCHEMBL2697040 0.86 TSHR (0.84) TSHRCDC25BALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116634871-A Pesticidal compounds and compositions, methods of use and methods of preparation thereof 阿达玛马克西姆有限公司 2023-08-22 CN disclosed