SCHEMBL7741671

SCHEMBL7741671

CCOC(=O)c1cccc2cccc(C(=O)O)c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
CDC25B P30305 2/20 0.55
HSD17B10 Q99714 3/20 0.53
MAPT P10636 4/20 0.51
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
CDC25A P30304 1/20 0.51
CDC25C P30307 1/20 0.51
CYP1A2 P05177 2/20 0.50
ALOX15 P16050 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAPK10 P53779 1/20 0.48
PTK2B Q14289 1/20 0.48
NCOA1 Q15788 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL29064574 0.95 TSHR (0.62) TSHRCDC25BHSD17B10MAPTALDH1A1
SCHEMBL3681837 0.93 TSHR (0.68) TSHRCDC25BHSD17B10MAPTALDH1A1
SCHEMBL18526159 0.88 TSHR (0.66) TSHRCDC25BHSD17B10MAPTALDH1A1
SCHEMBL28289328 0.87 ALDH1A1 (0.62) TSHRCDC25BHSD17B10MAPTALDH1A1
SCHEMBL21845577 0.85 TSHR (0.61) TSHRCDC25BHSD17B10MAPTALDH1A1
SCHEMBL27412533 0.84 TSHR (0.64) TSHRHSD17B10MAPTALDH1A1KDM4E
SCHEMBL9794664 0.84 TSHR (0.59) TSHRHSD17B10MAPTALDH1A1CYP1A2
SCHEMBL954473 0.83 TSHR (0.59) TSHRCDC25BHSD17B10MAPTALDH1A1
SCHEMBL27483119 0.83 HSD17B10 (0.58) TSHRCDC25BHSD17B10MAPTALDH1A1
SCHEMBL27552378 0.83 HSD17B10 (0.53) TSHRCDC25BHSD17B10MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1093153-C Crystalline polymer blends containing low molecular weight poly (phenylene ether) resin GEN ELECTRIC (US) 2002-10-23 CN claimed
CN-1174214-A Crystalline polymer blends containing low molecular weight poly (phenylene ether) resin GEN ELECTRIC (US) 1998-02-25 CN claimed
CN-1047318-A POLYMERIC FILM ICI PLC (GB) 1990-11-28 CN claimed
CN-109563009-A Alkene oligomerization process 公共型股份公司希布尔控股 2019-04-02 CN disclosed
CN-105121565-A Photocurable coating composition, coating film using same and polarizing plate DONGWOO FINE CHEM CO LTD 2015-12-02 CN disclosed
CN-103443087-B Polymerizable compound, polymerizable liquid crystal composition, polymeric compound, and film FUJIFILM CORP 2015-04-08 CN disclosed
CN-103781755-A Polymerizable liquid crystal compound, polymerizable composition, polymer material, and film FUJI PHOTO FILM CO LTD 2014-05-07 CN disclosed
CN-103443087-A Polymerizable compound, polymerizable liquid crystal composition, polymeric compound, and film FUJIFILM CORP 2013-12-11 CN disclosed
CN-100334174-C Composition for forming matte layer, release sheet, and synthetic leather DAINIPPON PRINTING CO LTD (JP) 2007-08-29 CN disclosed
CN-1485387-A Composition for forming matte layer, release sheet, and synthetic leather ���ձ�ӡˢ��ʽ���� 2004-03-31 CN disclosed
CN-1098124-C Oxidation catalyst system and process for oxidation with the same DAICEL CHEM (JP) 2003-01-08 CN disclosed
US-6238842-B1 SUITABLE FOR USE WITH AN EXPOSURE LIGHT HAVING A WAVELENGTH OF 250 NM OR SHORTER, ESPECIALLY 220 NM OR SHORTER; ACID GENERATING COMPOUND; RESIN HAVING MONOVALENT POLYALICYCLIC GROUPS FUJI PHOTO FILM CO., LTD. (JP) 2001-05-29 US disclosed
CN-1185757-A Oxidation catalyst system and oxidation process using the same DAICEL CHEM (JP) 1998-06-24 CN disclosed
CN-1035432-C Catalyst and method for purifying a crude terephthalic acid, isophthalic acid or naphthalene dicarboxylic acid AMOCO CORP (US) 1997-07-16 CN disclosed
CN-1151992-A (Co) polymers based on vinyl units and use thereof in electroluminescent arrangements BAYER AG (DE) 1997-06-18 CN disclosed
CN-1032015-C Styrene polymer composition IDEMITSU KOSAN CO (JP) 1996-06-12 CN disclosed
CN-1050886-A STYRENE POLYMER COMPOSITION IDEMITSU KOSAN CO (JP) 1991-04-24 CN disclosed
CN-1047318-A POLYMERIC FILM ICI PLC (GB) 1990-11-28 CN disclosed