Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 18/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064670 | 0.88 | TXNRD1 (0.40) | TXNRD1MAPTMAPK1SMN1; SMN2XDH | |
| SCHEMBL29064675 | 0.85 | TXNRD1 (0.43) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL29064683 | 0.84 | TXNRD1 (0.42) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL16470345 | 0.84 | MAPT (0.42) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL16470427 | 0.84 | TXNRD1 (0.42) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL29064666 | 0.83 | TXNRD1 (0.41) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL29064668 | 0.82 | TXNRD1 (0.42) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL29064662 | 0.81 | TXNRD1 (0.41) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL29064671 | 0.79 | TXNRD1 (0.38) | TXNRD1MAPTMAPK1XDHGSR | |
| SCHEMBL29203928 | 0.77 | TXNRD1 (0.43) | TXNRD1MAPTMAPK1XDHGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265460-B | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-116265460-B | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |