Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29530372 | 0.84 | MKNK2 (0.44) | MKNK2ABCB1MKNK1CNR2GSK3B | |
| SCHEMBL24335569 | 0.84 | MKNK2 (0.44) | MKNK2ABCB1MKNK1CNR2GSK3B | |
| SCHEMBL29064869 | 0.82 | MKNK1 (0.43) | MKNK2ABCB1MKNK1CNR2CLK2 | |
| SCHEMBL24335570 | 0.80 | HDAC1 (0.51) | MKNK2MKNK1GSK3BDYRK3JAK2 | |
| Hydrochloric Acid SCHEMBL30516488 | 0.79 | HDAC1 (0.50) | MKNK2MKNK1GSK3BDYRK3JAK2 | |
| Hydrochloric Acid SCHEMBL29064840 | 0.79 | HDAC1 (0.50) | MKNK2MKNK1GSK3BDYRK3JAK2 | |
| SCHEMBL2465121 | 0.76 | ABCB1 (0.57) | MKNK2ABCB1MKNK1PIM1HDAC1 | |
| SCHEMBL28842381 | 0.74 | HDAC1 (0.49) | MKNK2ABCB1MKNK1HDAC1KMO | |
| SCHEMBL7466534 | 0.72 | ABCB1 (0.64) | ABCB1 | |
| SCHEMBL24335577 | 0.71 | NAMPT (0.41) | MKNK2ABCB1MKNK1CNR2CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |