Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24335577 | 0.90 | NAMPT (0.41) | MKNK1MKNK2CNR2ABCB1DYRK1A | |
| SCHEMBL24359424 | 0.83 | MKNK1 (0.39) | MKNK1MKNK2CNR2DYRK1AWNT1 | |
| SCHEMBL29064834 | 0.82 | MKNK2 (0.47) | MKNK1MKNK2CNR2ABCB1DYRK1A | |
| SCHEMBL29580299 | 0.80 | ABCB1 (0.48) | ABCB1ABCC1CYP11B1CYP11B2 | |
| SCHEMBL29530372 | 0.76 | MKNK2 (0.44) | MKNK1MKNK2CNR2ABCB1DYRK1A | |
| SCHEMBL24335569 | 0.76 | MKNK2 (0.44) | MKNK1MKNK2CNR2ABCB1DYRK1A | |
| SCHEMBL31096195 | 0.70 | KDM4E (0.49) | MKNK1MKNK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28842381 | 0.69 | HDAC1 (0.49) | MKNK1MKNK2ABCB1HTR6SLC2A1 | |
| SCHEMBL2465121 | 0.69 | ABCB1 (0.57) | MKNK1MKNK2ABCB1HDAC3HDAC1 | |
| SCHEMBL15823575 | 0.67 | SUCNR1 (0.41) | HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |