Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295725 | 1.00 | TDP1 (0.36) | TDP1NPC1RAB9AEZH2CASP3 | |
| SCHEMBL25166373 | 0.74 | TDP1 (0.45) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL29064919 | 0.71 | HSP90AB1 (0.45) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL25166338 | 0.71 | TDP1 (0.40) | TDP1NPC1RAB9AEZH2CASP3 | |
| SCHEMBL3205153 | 0.70 | HSP90AB1 (0.44) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL25166327 | 0.65 | TDP1 (0.40) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL19531950 | 0.63 | TDP1 (0.37) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL19531947 | 0.63 | TDP1 (0.37) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL11418288 | 0.63 | ALDH1A1 (0.46) | TDP1NPC1RAB9AACMSD | |
| SCHEMBL25729525 | 0.61 | TDP1 (0.45) | TDP1NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |