SCHEMBL290654

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13048238	0.88	HDAC6 (0.34)	ABL1PIK3CGPTGDR2HDAC6POLQ
	SCHEMBL299739	0.86	ABL1 (0.33)	ABL1PIK3CGHSD17B1HSD17B2
	SCHEMBL290931	0.85	ABL1 (0.31)	ABL1PIK3CGPOLQCDC7DBF4
	SCHEMBL290708	0.85	ABL1 (0.33)	ABL1PIK3CGPOLQ
	SCHEMBL3749533	0.84	HDAC6 (0.31)	ABL1PIK3CGHDAC6
	SCHEMBL255154	0.83	KDM4E (0.46)	—
	SCHEMBL13048489	0.83	PIK3CG (0.34)	ABL1PIK3CGPTGDR2CYP11B2
	SCHEMBL13047434	0.82	ABL1 (0.32)	ABL1PIK3CGPTGDR2HSD17B1HSD17B2
	SCHEMBL13074524	0.82	HCAR2 (0.37)	ABL1PIK3CGPTGDR2POLQHSD17B1
	SCHEMBL3742278	0.81	ABL1 (0.33)	ABL1PIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.