Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA7 | P43166 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065453 | 0.76 | NPSR1 (0.38) | NPSR1KDM4ELMNAGAAXDH | |
| SCHEMBL6645420 | 0.76 | NPSR1 (0.34) | NPSR1KDM4ELMNAGAAPOLB | |
| SCHEMBL29065452 | 0.74 | NPSR1 (0.44) | NPSR1KDM4ELMNAGAAXDH | |
| SCHEMBL28474643 | 0.72 | NPSR1 (0.34) | NPSR1KDM4ELMNAGAAXDH | |
| SCHEMBL6414618 | 0.71 | TSHR (0.37) | NPSR1KDM4ELMNAGAAXDH | |
| SCHEMBL28296128 | 0.70 | TSHR (0.35) | NPSR1KDM4ELMNAGAATDP1 | |
| SCHEMBL31435414 | 0.68 | NPSR1 (0.34) | NPSR1KDM4ELMNAGAAXDH | |
| SCHEMBL28296127 | 0.68 | NPSR1 (0.34) | NPSR1KDM4ELMNAGAAXDH | |
| SCHEMBL6198951 | 0.67 | — | — | |
| SCHEMBL20013576 | 0.67 | CA12 (0.33) | NPSR1KDM4ELMNAGAAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490069-A | STAT degradation agent and application thereof | 凯麦拉医疗公司 | 2023-07-25 | — | — | CN | disclosed |