Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA7 | P43166 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065453 | 0.82 | NPSR1 (0.38) | NPSR1KDM4EXDHTDP1LMNA | |
| SCHEMBL23833210 | 0.79 | — | — | |
| SCHEMBL31435414 | 0.74 | NPSR1 (0.34) | NPSR1KDM4EXDHTDP1LMNA | |
| SCHEMBL29065452 | 0.73 | NPSR1 (0.44) | NPSR1KDM4EXDHTDP1LMNA | |
| SCHEMBL29065451 | 0.72 | NPSR1 (0.35) | NPSR1KDM4EXDHTDP1LMNA | |
| SCHEMBL30415854 | 0.70 | NPSR1 (0.34) | NPSR1KDM4ETDP1CA12CA1 | |
| SCHEMBL7388925 | 0.69 | NPSR1 (0.33) | NPSR1KDM4EALDH1A1TSHR | |
| SCHEMBL7388927 | 0.69 | NPSR1 (0.33) | NPSR1KDM4EALDH1A1TSHR | |
| SCHEMBL28296127 | 0.67 | NPSR1 (0.34) | NPSR1KDM4EXDHTDP1LMNA | |
| SCHEMBL6198951 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116490069-A | STAT degradation agent and application thereof | 凯麦拉医疗公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-107709305-B | Novel compound | 葛兰素史克知识产权开发有限公司 | 2020-09-29 | — | — | CN | disclosed |