SCHEMBL29065641

SCHEMBL29065641

O=Cc1ccc(-c2cn(Cc3ccccc3)nn2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.72
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
TEK Q02763 2/20 0.58
EPHB4 P54760 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
KDR P35968 4/20 0.56
GSK3B P49841 4/20 0.56
FLT3 P36888 1/20 0.56
PTGS2 P35354 1/20 0.56
SIRT2 Q8IXJ6 1/20 0.53
NAMPT P43490 1/20 0.53
ROCK2 O75116 4/20 0.52
CDK2 P24941 4/20 0.52
PIM1 P11309 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15836586 0.88 CYP19A1 (0.93) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL1165644 0.85 CYP19A1 (0.67) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL935182 0.85 CYP19A1 (1.00) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL28585317 0.82 CYP19A1 (0.81) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL12535881 0.81 NPC1 (0.88) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL2192331 0.81 CYP19A1 (0.79) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL28207545 0.81 CYP19A1 (0.79) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL16539592 0.81 CYP19A1 (0.79) CYP19A1NPC1RAB9ATEKEPHB4
SCHEMBL28529410 0.79 CYP19A1 (0.77) CYP19A1NPC1RAB9ATEKEPHB4
Acetic Acid SCHEMBL28328686 0.79 CYP19A1 (0.82) CYP19A1NPC1RAB9ATEKEPHB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113117724-B Recoverable supported Au52Cu72 (SR) 55 cluster catalyst and application thereof 安徽大学 2023-09-08 CN disclosed