SCHEMBL935182

SCHEMBL935182

c1ccc(Cn2cc(-c3ccccc3)nn2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 1.00
NPC1 O15118 2/20 0.79
RAB9A P51151 2/20 0.79
EPHB4 P54760 3/20 0.70
TEK Q02763 2/20 0.70
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
CASP3 P42574 1/20 0.70
SENP8 Q96LD8 1/20 0.70
SENP7 Q9BQF6 1/20 0.70
SENP6 Q9GZR1 1/20 0.70
KDR P35968 5/20 0.68
PTGS2 P35354 1/20 0.68
GSK3B P49841 4/20 0.64
FLT3 P36888 1/20 0.64
HDAC8 Q9BY41 2/20 0.62
HDAC6 Q9UBN7 2/20 0.62
HDAC3 O15379 1/20 0.62
HDAC4 P56524 1/20 0.62
HDAC1 Q13547 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15836586 0.96 CYP19A1 (0.93) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL12022166 0.91 CYP19A1 (0.84) CYP19A1NPC1RAB9AEPHB4TEK
Acetic Acid SCHEMBL28328686 0.91 CYP19A1 (0.82) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL22510634 0.90 CYP19A1 (0.82) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL28585317 0.90 CYP19A1 (0.81) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL16539592 0.89 CYP19A1 (0.79) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL16206204 0.89 CYP19A1 (0.79) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL12535881 0.89 NPC1 (0.88) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL2192331 0.89 CYP19A1 (0.79) CYP19A1NPC1RAB9AEPHB4TEK
SCHEMBL28524032 0.89 CYP19A1 (0.79) CYP19A1NPC1RAB9AEPHB4TEK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199557-A1 METHODS OF MAKING 1-BENZYL-4-PHENYL-1H-1,2,3-TRIAZOLE (BPT) AND BPT COATED STRUCTURES UNIV TEXAS (US) 2024-06-20 US claimed
CN-109745983-B Preparation method and application of copper nanoparticles with stable graphene quantum dots 三峡大学 2021-10-19 CN claimed
CN-108671961-A A kind of ruthenium complex photochemical catalyst, preparation method and applications 三峡大学 2018-10-19 CN claimed
WO-2017046813-A1 FLUORESCENT CYCLOMETALATED Ir (III) COMPLEXES AND FORMULATIONS/ COMPOSITIONS COMPRISING THE SAME GUPTA PARNA (IN) 2017-03-23 WO claimed
CN-103992354-A Synthesis method of triazole ruthenium complex and single crystal thereof UNIV EAST CHINA SCIENCE & TECH 2014-08-20 CN claimed
CN-101704793-A 5-alkenyl-1, 4-disubstituted-1, 2, 3-triazole compound, preparation method and application thereof UNIV SOUTH CHINA TECH 2010-05-12 CN claimed
CN-119972200-A Method for improving copper ion catalytic click reaction activity by ionizing radiation and application 北京师范大学 2025-05-13 CN disclosed
CN-119746934-A Copper catalyst and preparation method, application and application method thereof 天津大学 2025-04-04 CN disclosed
CN-118307488-A Phenyl-1, 2, 3-triazole stilbene compound and preparation method and application thereof 华南理工大学 2024-07-09 CN disclosed
CN-118290354-A Preparation method of 1, 4-disubstituted triazole 大连理工大学 2024-07-05 CN disclosed
US-20240199557-A1 METHODS OF MAKING 1-BENZYL-4-PHENYL-1H-1,2,3-TRIAZOLE (BPT) AND BPT COATED STRUCTURES UNIV TEXAS (US) 2024-06-20 US disclosed
US-20240199557-A1 METHODS OF MAKING 1-BENZYL-4-PHENYL-1H-1,2,3-TRIAZOLE (BPT) AND BPT COATED STRUCTURES UNIV TEXAS (US) 2024-06-20 US disclosed
US-20240199557-A1 METHODS OF MAKING 1-BENZYL-4-PHENYL-1H-1,2,3-TRIAZOLE (BPT) AND BPT COATED STRUCTURES UNIV TEXAS (US) 2024-06-20 US disclosed
US-20110172417-A1 Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2011-07-14 US disclosed
WO-2011009934-A1 TRIS(1,2,3-TRIAZOL-4-YL)METHANE ORGANOMETALLIC COMPOUNDS AS CATALYSTS AND PROCESSES USING THEM. INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) 2011-01-27 WO disclosed
WO-2011009934-A1 TRIS(1,2,3-TRIAZOL-4-YL)METHANE ORGANOMETALLIC COMPOUNDS AS CATALYSTS AND PROCESSES USING THEM. INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) 2011-01-27 WO disclosed
US-20100197871-A1 LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS THE SCRIPPS RESEARCH INSTITUTE 2010-08-05 US disclosed
CN-101704793-A 5-alkenyl-1, 4-disubstituted-1, 2, 3-triazole compound, preparation method and application thereof UNIV SOUTH CHINA TECH 2010-05-12 CN disclosed
WO-2009038685-A1 LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2009-03-26 WO disclosed
US-20090023916-A1 TETRAZINE-BASED BIO-ORTHOGONAL COUPLING REAGENTS AND METHODS UNIVERSITY OF DELAWARE (US) 2009-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172417-A1 Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof AOC3, AOC2, USP13 CYP19A1 2195/4885NPC1 3004/4885RAB9A 3597/4885
US-20100197871-A1 LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS AOC2, AOC1, AOC3 CYP19A1 185/4885NPC1 2233/4885RAB9A 4347/4885
US-20240199557-A1 METHODS OF MAKING 1-BENZYL-4-PHENYL-1H-1,2,3-TRIAZOLE (BPT) AND BPT COATED STRUCTURES BPNT1, BPTF, BRI3BP CYP19A1 2771/4885NPC1 974/4885RAB9A 3539/4885
US-20090023916-A1 TETRAZINE-BASED BIO-ORTHOGONAL COUPLING REAGENTS AND METHODS SKIC8, TCOF1, TTI2 CYP19A1 4408/4885NPC1 4841/4885RAB9A 4119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.